SYNTHESIS OF MACROCYCLIC PROPARGYLIC ALCOHOLS BY ENE-TYPE CYCLIZATION OF UNSATURATED ACETYLENIC ALDEHYDES

被引：18

作者：

MARSHALL, JA

ANDERSEN, MW

机构：

[1] Department of Chemistry and Biochemistry, The University of South Carolina, Columbia

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1992年 / 57卷 / 10期

关键词：

D O I：

10.1021/jo00036a002

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Ene type cyclizations of ynals 6,21, and 30 can be effected by EtAlCl2 in CH2Cl2 at -78-degrees-C to afford 14-and 12-membered homoallylic propargylic alcohols in 66-89% yield.

引用

页码：2766 / 2768

页数：3

共 13 条

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