PIEZOELECTRIC INDUCTION OF BONE FORMATION: ULTRASTRUCTURAL OBSERVATIONS

被引：9

作者：

Ficat, J. J. ^{[1
]}

Thiechart, M. ^{[1
]}

Ficat, P. ^{[1
]}

Lacabanne, C. ^{[1
]}

Micheron, F. ^{[2
]}

Bab, I. ^{[3
]}

机构：

[1] Univ Toulouse 3, F-31062 Toulouse, France

[2] LCR Thomson, CSF, F-91401 Orsay, France

[3] Hebrew Univ Jerusalem, Div Oral Pathol, Hadassah Sch Dent Med, IL-91905 Jerusalem, Israel

来源：

FERROELECTRICS | 1984年 / 60卷 / 01期

关键词：

D O I：

10.1080/00150198408017532

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

We have recently shown that bimorph piezoelectric PVDF films induce formation of periosteal bone in vivo and attributed this phenomenon to a piezoelectric effect. In the present study films were implanted in rabbits to encircle the femoral diaphysis. Specimens obtained after 6 and 12 days were subjected to routine processing for electron microscopy as well as fixation using the Ka-pyroantimonate technique. The electron micrographs revealed that initial osteoblastic differentiation and formation of collagenous matrix were followed by Ca accumulation in mitochondria. Calcification of the matrix progressed with deposition of mineralizing nodules and their fusion to form larger calcified masses. This was associated with disappearance of the pyroantimonate positive material from mitochondria. These ultrastructural observations confirm that bimorph films induce bone formation and disclose some features of the calcification process of the osseous callus.

引用

页码：313 / 316

页数：4

共 8 条

[1] ELECTRON-MICROSCOPIC PYROANTIMONATE STUDIES OF MATRIX VESICLES AND MITOCHONDRIA IN THE RACHITIC GROWTH PLATE [J].