POSTSYNTHETIC TRANSFORMATIONS OF OLIGODEOXYNUCLEOTIDES ORIGINATED AT 6-METHYLTHIO-PURINE SITE

被引：10

作者：

BURDZY, A

SKALSKI, B

BIALA, E

KOWALEWSKI, A

PASZYC, S

ADAMIAK, RW

机构：

[1] POLISH ACAD SCI,INST BIOORGAN CHEM,POZNAN,POLAND

[2] ADAM MICKIEWICZ UNIV POZNAN,FAC CHEM,POZNAN,POLAND

来源：

NUCLEOSIDES & NUCLEOTIDES | 1995年 / 14卷 / 3-5期

关键词：

D O I：

10.1080/15257779508012515

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

New route to oligodeoxynucleotides labeled with fluorescent luminarine was explored. Regioselective oxidation of 6-methylthio-purines to 6-methylsulphoxides reactive toward pyridine was achieved. Upon UV irradiation of 6-pyridinium-purines oligonucleotide cleavage instead of phototransformation to luminarine was observed.

引用

页码：979 / 982

页数：4

共 9 条

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