YTTRIUM TRIFLATE-CATALYZED ADDITION OF LITHIUM ENOLATES TO 1,2-EPOXIDES - EFFICIENT SYNTHESIS OF GAMMA-HYDROXY KETONES

被引:31
作者
CROTTI, P
DIBUSSOLO, V
FAVERO, L
MACCHIA, F
PINESCHI, M
机构
[1] Dipartimento di Chimica Bioorganica, Università di Pisa, 56126 Pisa
关键词
D O I
10.1016/S0040-4039(00)78266-9
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A simple, efficient method is described for the synthesis of gamma-hydroxy ketones by the direct opening of 1,2-epoxides with lithium enolates derived from simple ketones in anhydrous toluene, in the presence of Y(OTf)(3).
引用
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页码:6537 / 6540
页数:4
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