SYNTHESIS OF NOVEL CROSS-LINKED BIS-LEXITROPSINS

被引：21

作者：

ALSAID, NH ^{[1
]}

LOWN, JW ^{[1
]}

机构：

[1] UNIV ALBERTA,DEPT CHEM,EDMONTON T6G 2G2,AB,CANADA

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 41期

关键词：

D O I：

10.1016/S0040-4039(00)78347-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of covalently cross-linked bis-lexitropsins 14, 15 and 16 designed to bind to specific nucleotide sequences in the minor groove of double-helical DNA is described.

引用

页码：7577 / 7580

页数：4

共 11 条

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[7] DESIGN OF A COVALENT PEPTIDE HETERODIMER FOR SEQUENCE-SPECIFIC RECOGNITION IN THE MINOR-GROOVE OF DOUBLE-HELICAL DNA
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[8] ENHANCED SEQUENCE-SPECIFIC RECOGNITION IN THE MINOR-GROOVE OF DNA BY COVALENT PEPTIDE DIMERS - BIS(PYRIDINE-2-CARBOXAMIDONETROPSIN)(CH2)3-6
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[9] ANTIPARALLEL SIDE-BY-SIDE HETERODIMER FOR SEQUENCE-SPECIFIC RECOGNITION IN THE MINOR GROOVE OF DNA BY A DISTAMYCIN 1-METHYLIMIDAZOLE-2-CARBOXAMIDE-NETROPSIN PAIR
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