INVITRO COMBINATION OF MECILLINAM WITH CEPHRADINE OR AMOXYCILLIN FOR ORGANISMS RESISTANT TO SINGLE AGENTS

被引:10
作者
CHATTOPADHYAY, B [1 ]
HALL, I [1 ]
机构
[1] WHIPPS CROSS HOSP,DEPT MICROBIOL,LONDON E11 1NR,ENGLAND
关键词
D O I
10.1093/jac/5.5.549
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Of 36 multi-resistant Gram-negative bacilli isolated from different cases of urinary tract infection, 18 strains of Ercherichia coli, klebsiella, enterobacter, proteus, providencia and serratia with the exception of Acinetobacter species showed synergy when mecillinam was combined with cephradine or amoxycillin the ratio of 1:1. Combination with cephradine was synergistic on sixteen Occasions and amoxycillin on six. Synergy, which might have clinical relevance, was demonstrated only when the test organism was either fully or moderately sensitive to one of the two antibiotics combined but not when resistant to both. © 1979, by The British Society for Antimicrobial Chemotherapy.
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页码:549 / &
相关论文
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