UNIFORM DEPTH DOSE DISTRIBUTION FOR BIOLOGICAL IRRADIATION USING NEGATIVE PIONS

被引：6

作者：

LAM, GKY ^{[1
]}

HENKELMAN, RM ^{[1
]}

HARRISON, RW ^{[1
]}

SKARSGARD, LD ^{[1
]}

PALCIC, B ^{[1
]}

机构：

[1] UNIV BRITISH COLUMBIA,FAC BATHO BIOMED,TRIUMF,VANCOUVER V6T 1W5,BC,CANADA

来源：

PHYSICS IN MEDICINE AND BIOLOGY | 1979年 / 24卷 / 06期

关键词：

D O I：

10.1088/0031-9155/24/6/014

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

A simple, flexible technique has been developed to generate uniform depth dose profiles for the biomedical pion beam at TRIUMF using dynamic momentum control and linear programming. Either the entrance dose or the irradiation time required for a certain dose over the uniform region can be minimised. The dynamic momentum control can operate automatically under computer control even with a highly unstable beam. Cell survival profiles have been obtained for this uniform dose distribution using the gelatin technique. The RBE increases with increasing depth through the uniform dose region.

引用

页码：1243 / 1249

页数：7

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