PROTECTION AGAINST BRUCELLA-MELITENSIS OR BRUCELLA-ABORTUS IN MICE WITH IMMUNOGLOBULIN-G (IGG), IGA, AND IGM MONOCLONAL-ANTIBODIES SPECIFIC FOR A COMMON EPITOPE SHARED BY THE BRUCELLA A AND M SMOOTH LIPOPOLYSACCHARIDES

被引：67

作者：

CLOECKAERT, A

JACQUES, I

DEWERGIFOSSE, P

DUBRAY, G

LIMET, JN

机构：

[1] INRA,PATHOL INFECT & IMMUNOL LAB,F-37380 NOUZILLY,FRANCE

[2] FAC UNIV NOTRE DAME PAIX,B-5000 NAMUR,BELGIUM

来源：

INFECTION AND IMMUNITY | 1992年 / 60卷 / 01期

关键词：

D O I：

10.1128/IAI.60.1.312-315.1992

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Mice passively immunized prior to a challenge infection with immunoglobulin G (IgG) and IgM monoclonal antibodies (MAbs) specific for a common epitope of both A- and M-dominant strains had viable Brucella abortus 544 or Brucella melitensis H38 counts in the spleen reduced to the same extent as did mice passively immunized with MAbs specific for either the A or the M epitope. The IgA MAb was not effective.

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页码：312 / 315

页数：4

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