SINGLE CAPRIPOXVIRUS RECOMBINANT VACCINE FOR THE PROTECTION OF CATTLE AGAINST RINDERPEST AND LUMPY SKIN-DISEASE

被引：83

作者：

ROMERO, CH ^{[1
]}

BARRETT, T ^{[1
]}

EVANS, SA ^{[1
]}

KITCHING, RP ^{[1
]}

GERSHON, PD ^{[1
]}

BOSTOCK, C ^{[1
]}

BLACK, DN ^{[1
]}

机构：

[1] AFRC, INST ANIM HLTH, PIRBRIGHT LAB, WOKING GU24 0NF, SURREY, ENGLAND

来源：

VACCINE | 1993年 / 11卷 / 07期

基金：

英国惠康基金;

关键词：

RINDERPEST; CAPRIPOX; RECOMBINANT VACCINE; FUSION GENE;

D O I：

10.1016/0264-410X(93)90258-Y

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A recombinant capripoxvirus has been constructed containing a full-length cDNA of the fusion protein gene of rinderpest virus. The gene was inserted in the thymidine kinase gene of the capripox genome under the control of the vaccinia virus major late promoter p11 together with the Escherichia coli gpt gene in the opposite orientation under the control of the vaccinia early/late promoter p7.5. A vaccine prepared from this recombinant virus protected cattle against clinical rinderpest after a lethal challenge with a virulent virus isolate. In addition, the vaccine protected the cattle against lumpy skin disease.

引用

页码：737 / 742

页数：6

共 27 条

[1] IMMUNIZATION WITH A VACCINIA RECOMBINANT EXPRESSING THE F-PROTEIN PROTECTS RABBITS FROM CHALLENGE WITH A LETHAL DOSE OF RINDERPEST VIRUS [J].

BARRETT, T ;

BELSHAM, GJ ;

SUBBARAO, SM ;

EVANS, SA .

VIROLOGY, 1989, 170 (01) :11-18

[2] SAFETY OF RECOMBINANT VACCINIA VACCINES [J].

BAXBY, D .

LANCET, 1991, 337 (8746) :913-913

[3] IMMUNE-RESPONSE AND PROTECTION OF CATTLE AND PIGS GENERATED BY A VACCINIA VIRUS RECOMBINANT EXPRESSING THE F-PROTEIN OF RINDERPEST VIRUS [J].

BELSHAM, GJ ;

ANDERSON, EC ;

MURRAY, PK ;

ANDERSON, J ;

BARRETT, T .

VETERINARY RECORD, 1989, 124 (25) :655-658

[4] GENOMIC RELATIONSHIP BETWEEN CAPRIPOXVIRUSES [J].

BLACK, DN ;

HAMMOND, JM ;

KITCHING, RP .

VIRUS RESEARCH, 1986, 5 (2-3) :277-292

[5] INSERTION OF THE FUSION GENE FROM NEWCASTLE-DISEASE VIRUS INTO A NONESSENTIAL REGION IN THE TERMINAL REPEATS OF FOWLPOX VIRUS AND DEMONSTRATION OF PROTECTIVE IMMUNITY INDUCED BY THE RECOMBINANT [J].

BOURSNELL, MEG ;

GREEN, PF ;

CAMPBELL, JIA ;

DEUTER, A ;

PETERS, RW ;

TOMLEY, FM ;

SAMSON, ACR ;

CHAMBERS, P ;

EMMERSON, PT ;

BINNS, MM .

JOURNAL OF GENERAL VIROLOGY, 1990, 71 :621-628

[6] CONSTRUCTION OF RECOMBINANT FOWLPOX VIRUSES AS VECTORS FOR POULTRY VACCINES [J].

BOYLE, DB ;

COUPAR, BEH .

VIRUS RESEARCH, 1988, 10 (04) :343-356

[7] A DOMINANT SELECTABLE MARKER FOR THE CONSTRUCTION OF RECOMBINANT POXVIRUSES [J].

BOYLE, DB ;

COUPAR, BEH .

GENE, 1988, 65 (01) :123-128

[8]

CHOMCZYNSKI P, 1987, ANAL BIOCHEM, V162, P156, DOI 10.1016/0003-2697(87)90021-2

[9] INVITRO MUTAGENESIS OF THE PROMOTER REGION FOR A VACCINIA VIRUS GENE - EVIDENCE FOR TANDEM EARLY AND LATE REGULATORY SIGNALS [J].

COCHRAN, MA ;

PUCKETT, C ;

MOSS, B .

JOURNAL OF VIROLOGY, 1985, 54 (01) :30-37

[10] PROTECTION OF MICE FROM FATAL MEASLES ENCEPHALITIS BY VACCINATION WITH VACCINIA VIRUS RECOMBINANTS ENCODING EITHER THE HEMAGGLUTININ OR THE FUSION PROTEIN [J].

DRILLIEN, R ;

SPEHNER, D ;

KIRN, A ;

GIRAUDON, P ;

BUCKLAND, R ;

WILD, F ;

LECOCQ, JP .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (04) :1252-1256

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