BIOSYNTHESIS OF IRIDOIDS IN SYRINGA AND FRAXINUS - CARBOCYCLIC IRIDOID PRECURSORS

被引：22

作者：

DAMTOFT, S

FRANZYK, H

JENSEN, SR

机构：

[1] Department of Organic Chemistry, The Technical University of Denmark

来源：

PHYTOCHEMISTRY | 1995年 / 40卷 / 03期

关键词：

FRAXINUS EXCELSIOR; SYRINGA JOSIKAEA; S-VULGARIS; OLEACEAE; SECOIRIDOID GLUCOSIDES; BIOSYNTHESIS; OLEOSIDES; OLEUROPEIN;

D O I：

10.1016/0031-9422(95)00210-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Feeding experiments with deuterium-labelled precursors to Fraxinus excelsior, Syringa josikaea and S. vulgaris have shown that the biosynthesis of the oleoside-type secoiridoids (e.g. oleuropein) proceeds via iridodial, iridotrial, deoxy-loganic acid aglucon and deoxy-loganic acid. Hydroxylation of the 7 alpha-position is followed by oxidation and methylation of C-11 to give 7-ketologanin, the last carbocyclic iridoid precursor of the oleosides. The sequences of the steps between deoxy-loganic acid and 7-ketologanin may differ with plant species and time of year. 8-Epi-kingisidic acid and 8-epi-kingiside can be formed from 8-ketologanic acid (and its methyl ester). The secoiridoids, fliederoside and lilacoside, from S. vulgaris have been characterized.

引用

页码：785 / 792

页数：8

共 7 条

[1]

BREINHOLT J, 1992, PHYTOCHEMISTRY, V31, P795, DOI 10.1016/0031-9422(92)80017-9

[2] BIOSYNTHESIS OF SECOIRIDOID GLUCOSIDES IN OLEACEAE [J].