STRUCTURE OF THE HUMAN PROGESTERONE-RECEPTOR GENE

被引：74

作者：

MISRAHI, M

VENENCIE, PY

SAUGIERVEBER, P

SAR, S

DESSEN, P

MILGROM, E

机构：

[1] HOP BICETRE,CHU BICETRE 3EME NIVEAU,UNITE HORMONES & REPROD,INSERM,U135,78 RUE GEN LECLERC,F-94275 LE KREMLIN BICETR,FRANCE

[2] ECOLE POLYTECH,CNRS,UA 240,BIOCHIM LAB,F-91128 PALAISEAU,FRANCE

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1993年 / 1216卷 / 02期

关键词：

PROGESTERONE RECEPTOR GENE; STEROID HORMONE RECEPTOR GENE; INTRANUCLEAR RECEPTOR GENE; SEQUENCE ANALYSIS; (HUMAN);

D O I：

10.1016/0167-4781(93)90156-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The complete organization of the human progesterone receptor (hPR) gene has been determined. It spans over 90 kbp and contains eight exons. The first exon encodes the N-terminal part of the receptor. The DNA binding domain is encoded by two exons, each exon corresponding to one zinc finger. The steroid binding domain is encoded by five exons. The nucleotide sequence of 1144 bp of the 5' flanking region has been determined.

引用

页码：289 / 292

页数：4

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