EVIDENCE FOR PARA-HYDROXYLATION OF N-ETHYL-N-METHYLANILINE

被引：12

作者：

GORROD, JW

PATTERSON, LH

机构：

来源：

XENOBIOTICA | 1980年 / 10卷 / 7-8期

关键词：

D O I：

10.3109/00498258009033794

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：603 / 610

页数：8

共 12 条

[1] METABOLIC N-OXIDATION OF SECONDARY AND PRIMARY AROMATIC-AMINES AS A ROUTE TO RING HYDROXYLATION, TO VARIOUS N-OXYGENATED PRODUCTS, AND TO DEALKYLATION OF SECONDARY-AMINES [J].

BECKETT, AH ;

BELANGER, PM .

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[2] METABOLISM OF ANILINE MUSTARD [N,N-DI-(2-CHLOROETHYL)ANILINE] [J].

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FARMER, PB ;

FOSTER, AB ;

GILSENAN, AM ;

JARMAN, M ;

TISDALE, MJ .

BIOCHEMICAL PHARMACOLOGY, 1973, 22 (16) :1971-1980

[3] MIGRATION OF DEUTERIUM DURING HYDROXYLATION OF AROMATIC SUBSTRATES BY LIVER MICROSOMES .I. INFLUENCE OF RING SUBSTITUENTS [J].

DALY, J ;

JERINA, D ;

WITKOP, B .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1968, 128 (02) :517-&

[4] THIN-LAYER CHROMATOGRAPHIC-SEPARATION AND IDENTIFICATION OF TERTIARY AROMATIC-AMINES AND THEIR N-OXIDES [J].

DAMANI, LA ;

PATTERSON, LH ;

GORROD, JW .

JOURNAL OF CHROMATOGRAPHY, 1978, 155 (02) :337-348

[5] MICROSOMAL HYDROXYLATION OF ANILINE MUSTARD-D3[N,N-DI-(2-CHLOROETHYL)-2,4,6-TRIDEUTERIOANILINE] [J].

FARMER, PB ;

FOSTER, AB ;

JARMAN, M .

BIOMEDICAL MASS SPECTROMETRY, 1975, 2 (02) :107-111

[6] DIFFERENTIATION OF N-OXIDATION AND N-DEALKYLATION OF N-ETHYL-N-METHYLANILINE BY RABBIT LIVER-MICROSOMES AS DISTINCT METABOLIC ROUTES [J].

GORROD, JW ;

TEMPLE, DJ ;

BECKETT, AH .

XENOBIOTICA, 1975, 5 (08) :465-474

[7] METABOLISM OF N-ETHYL-N-METHYLANILINE BY RABBIT LIVER-MICROSOMES - MEASUREMENT OF METABOLITES BY GAS-LIQUID-CHROMATOGRAPHY [J].

GORROD, JW ;

TEMPLE, DJ ;

BECKETT, AH .

XENOBIOTICA, 1975, 5 (08) :453-463

[8] On the make-up of diethyl-anilin and diethyl-anilinoxide in animal bodies. [J].

Horn, F .

HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE, 1937, 249 :82-84

[9] URINARY METABOLITES OF N,N-DIMETHYLANILINE PRODUCED BY DOGS [J].

KIESE, M ;

RENNER, G .

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 1974, 283 (02) :143-150

[10]

KIESE M, 1971, XENOBIOTICA, V1, P241

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