INFLUENCE OF HUMAN RHEUMATOID FACTOR ON NUMBERS OF ANTIBODY-PRODUCING CELLS

被引：14

作者：

BROWN, JC

EPSTEIN, WV

机构：

[1] University of California Medical Center, San Francisco, California

[2] MRC Rheumatism Research Unit, Taplow

来源：

ARTHRITIS AND RHEUMATISM | 1969年 / 12卷 / 01期

关键词：

D O I：

10.1002/art.1780120102

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Human rheumatoid factor administered to mice 24 hours after intraperitoneal injection of human IgC as antigen causes a 68 per cent reduction in the numbers of spleen cells capable of forming rosettes with IgG‐coated sheep erythrocytes. Normal human macroglobulin does not cause such an inhibition of antibody‐producing cells. The inhibitory effect of rheumatoid macroglobulin appears immunologically specific. Copyright © 1969 American College of Rheumatology

引用

页码：1 / +

页数：1

共 34 条

[1] COMPETITION OF ANTIGENS [J].