SELECTIVE EXPOSURE OF MUCOPOLYSACCHARIDES IS INVOLVED IN MACROPHAGE PHYSIOLOGY

被引：11

作者：

DELROSSO, M ^{[1
]}

CAPPELLETTI, R ^{[1
]}

VANNUCCHI, S ^{[1
]}

ROMAGNANI, S ^{[1
]}

CHIARUGI, VP ^{[1
]}

机构：

[1] UNIV FLORENCE, SCH MED, INST GEN PATHOL, I-50134 FLORENCE, ITALY

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1979年 / 586卷 / 03期

关键词：

Cell surface; Macrophage; Mucopolysaccharide; Selective exposure;

D O I：

10.1016/0304-4165(79)90041-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Surface and intracellular mucopolysaccharides of guinea-pig peritoneal macrophages maintained in suspension and monolayer culture were studied. At least five classes of compound (hyaluronic acid, heparan sulfate, dermatan sulfate, chondroitin 4-sulfate and chondroitin 6-sulfate) were resolved and characterized by electrophoresis and enzymatic degradation. The results reported here suggest that modulation of mucopolysaccharide exposure is involved in macrophage physiology. The possible biological role of surface mucopolysaccharides in macrophage activity is discussed. © 1979.

引用

页码：512 / 517

页数：6

共 26 条

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