ENERGY DEPENDENT NUCLEOLYTIC PROCESSES ARE RESPONSIBLE FOR PRODUCTION OF MANY POST-IRRADIATION BREAKS IN L CELL DNA

被引：12

作者：

DALRYMPLE, GV

SANDERS, JL

MOSS, AJ

BAKER, ML

WILKINSON, KP

机构：

[1] Department of Radiology, University of Arkansas Medical Center Little Rock, AR

[2] Department of Biometry, University of Arkansas Medical Center Little Rock, AR

[3] Department of Physiology, Biophysics University, Arkansas Medical Center Little Rock, AR

[4] The Radiology Service Veterans Administration Hospital Little Rock, AR

[5] Radioisotopes Service Veterans Administration Hospital Little Rock, AR

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1969年 / 36卷 / 02期

关键词：

D O I：

10.1016/0006-291X(69)90327-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

L cells irradiated while in growth medium or in a balanced salts solution showed a rapid appearance of DNA breaks characterized by 5′ phosphoryl termini. Following irradiation, the number of breaks quickly reached a maximum, after which they were rapidly repaired. Dinitrophenol, an inhibitor of aerobic oxidative phosphorylation, prevented the DNA breaks from appearing. © 1969.

引用

页码：284 / +

页数：1

共 8 条

[1] STUDIES ON RADIATION-INDUCED BREAKDOWN OF DEOXYRIBONUCLEIC ACID IN ESCHERICHIA COLI 15T-L- [J].