CARBOCYCLIC ANALOGS OF NUCLEOSIDES VIA MODIFIED MITSUNOBU REACTIONS

被引:91
作者
JENNY, TF [1 ]
PREVISANI, N [1 ]
BENNER, SA [1 ]
机构
[1] SWISS FED INST TECHNOL,ORGAN CHEM LAB,CH-8092 ZURICH,SWITZERLAND
关键词
CARBOCYCLIC NUCLEOSIDES; MITSUNOBU REACTION; ANTIVIRAL NUCLEOSIDES; ANTISENSE NUCLEOTIDE ANALOGS;
D O I
10.1016/0040-4039(91)85031-Y
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A set of carbocyclic nucleoside analogs have been prepared using a novel modification of the Mitsunobu reaction. This approach helps solve an important synthetic problem in the preparation of carbocyclic analogs of nucleosides.
引用
收藏
页码:7029 / 7032
页数:4
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