AMIODARONE-INDUCED TORSADES-DE-POINTES - THE POSSIBLE FACILITATORY ROLE OF DIGOXIN

被引:13
作者
BAJAJ, BP [1 ]
BAIG, MW [1 ]
PERRINS, EJ [1 ]
机构
[1] GEN INFIRM,DEPT MED CARDIOL,LEEDS LS1 3EX,W YORKSHIRE,ENGLAND
关键词
AMIODARONE; TORSADES-DE-POINTES; DIGOXIN;
D O I
10.1016/0167-5273(91)90369-Z
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Poorly controlled supraventricular arrhythmias in a hypokalaemic 74 year old woman were treated with oral amiodarone. This caused torsades de pointes, and was preceded by marked prolongation of the QT interval. The induction of torsades de pointes by amiodarone is thought to be an idiosyncratic reaction to amiodarone itself which is facilitated by electrolytic abnormalities. The present case, however, indicates the possibility of a pro-arrhythmic effect secondary to an interaction between amiodarone and digoxin.
引用
收藏
页码:335 / 338
页数:4
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