GENETIC-EVIDENCE THAT PLACENTAL SITE TROPHOBLASTIC TUMORS CAN ORIGINATE FROM A HYDATIDIFORM MOLE OR A NORMAL CONCEPTUS

被引：46

作者：

FISHER, RA ^{[1
]}

PARADINAS, FJ ^{[1
]}

NEWLANDS, ES ^{[1
]}

BOXER, GM ^{[1
]}

机构：

[1] CHARING CROSS & WESTMINSTER MED SCH,DEPT HISTOPATHOL,LONDON W6 8RP,ENGLAND

来源：

BRITISH JOURNAL OF CANCER | 1992年 / 65卷 / 03期

关键词：

D O I：

10.1038/bjc.1992.72

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The genetic origin of two placental site trophoblastic tumours was established using a Y chromosome-specific and locus-specific minisatellite probes. A gestational origin was confirmed for both tumours. In one case the origin of the tumour was consistent with derivation from a normal female conceptus while the other was shown to arise from a homozygous complete hydatidiform mole, an abnormal conceptus more usually associated with the development of choriocarcinoma.

引用

页码：355 / 358

页数：4

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