BIOCHEMISTRY OF MULTIDRUG-RESISTANCE MEDIATED BY THE MULTIDRUG TRANSPORTER

被引：3483

作者：

GOTTESMAN, MM ^{[1
]}

PASTAN, I ^{[1
]}

机构：

[1] NCI,MOLEC BIOL LAB,BETHESDA,MD 20892

来源：

ANNUAL REVIEW OF BIOCHEMISTRY | 1993年 / 62卷

关键词：

CHEMOTHERAPY; CANCER; ATPASE; GENE THERAPY;

D O I：

10.1146/annurev.bi.62.070193.002125

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

[No abstract available]

引用

页码：385 / 427

页数：43

共 268 条

[1] CYCLIC AMP-DEPENDENT PROTEIN-KINASE REGULATES SENSITIVITY OF CELLS TO MULTIPLE-DRUGS [J].

ABRAHAM, I ;

HUNTER, RJ ;

SAMPSON, KE ;

SMITH, S ;

GOTTESMAN, MM ;

MAYO, JK .

MOLECULAR AND CELLULAR BIOLOGY, 1987, 7 (09) :3098-3106

[2]

AIHARA M, 1991, BLOOD, V77, P2079

[3] ISOLATION AND GENETIC-CHARACTERIZATION OF HUMAN KB-CELL LINES RESISTANT TO MULTIPLE-DRUGS [J].

AKIYAMA, SI ;

FOJO, A ;

HANOVER, JA ;

PASTAN, I ;

GOTTESMAN, MM .

SOMATIC CELL AND MOLECULAR GENETICS, 1985, 11 (02) :117-126

[4]

AMBUDKAR SV, 1990, J BIOL CHEM, V265, P12287

[5] BACTERIAL PERIPLASMIC TRANSPORT-SYSTEMS - STRUCTURE, MECHANISM, AND EVOLUTION [J].

AMES, GFL .

ANNUAL REVIEW OF BIOCHEMISTRY, 1986, 55 :397-425

[6]

ARCECI M, 1992, BLOOD, V33, pA2815

[7] THE GENE ENCODING MULTIDRUG RESISTANCE IS INDUCED AND EXPRESSED AT HIGH-LEVELS DURING PREGNANCY IN THE SECRETORY EPITHELIUM OF THE UTERUS [J].

ARCECI, RJ ;

CROOP, JM ;

HORWITZ, SB ;

HOUSMAN, D .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (12) :4350-4354

[8] MULTIDRUG RESISTANCE GENE-EXPRESSION IS CONTROLLED BY STEROID-HORMONES IN THE SECRETORY EPITHELIUM OF THE UTERUS [J].

ARCECI, RJ ;

BAAS, F ;

RAPONI, R ;

HORWITZ, SB ;

HOUSMAN, D ;

CROOP, JM .

MOLECULAR REPRODUCTION AND DEVELOPMENT, 1990, 25 (02) :101-109

[9] ALTERED PLASMA-MEMBRANE ULTRASTRUCTURE IN MULTIDRUG-RESISTANT CELLS [J].

ARSENAULT, AL ;

LING, V ;

KARTNER, N .

BIOCHIMICA ET BIOPHYSICA ACTA, 1988, 938 (02) :315-321

[10] DISCRETE MUTATIONS INTRODUCED IN THE PREDICTED NUCLEOTIDE-BINDING SITES OF THE MDR1 GENE ABOLISH ITS ABILITY TO CONFER MULTIDRUG RESISTANCE [J].

AZZARIA, M ;

SCHURR, E ;

GROS, P .

MOLECULAR AND CELLULAR BIOLOGY, 1989, 9 (12) :5289-5297

← 1 2 3 4 5 6 7 8 9 10 →