FLUOROMETRIC ANALYSIS OF POLYAMINES, HISTAMINE, AND 1-METHYLHISTAMINE

被引：41

作者：

PERINI, F

SADOW, JB

HIXSON, CV

机构：

[1] Biological Markers Laboratory, NCI Frederick Cancer Research Center, Frederick, MD 21701, P.O. Box B

来源：

ANALYTICAL BIOCHEMISTRY | 1979年 / 94卷 / 02期

关键词：

D O I：

10.1016/0003-2697(79)90386-5

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

This paper describes an automated cation-exchange chromatographic method for the simultaneous analysis of di- and polyamines, histamine, and its metabolite 1-methylhistamine. Recommendations for the selection of an effective system are made after evaluating sodium- and potassium-containing buffers, pH, temperature, column packings, and detection methods. The method can be used to analyze di- and polyamines in biological fluids, such as urine and tissue extracts, and may be useful for monitoring the effectiveness of cancer chemotherapy. © 1979.

引用

页码：431 / 439

页数：9

共 21 条

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