ACTIVATION OF THE NA+/K+/CL- COTRANSPORT SYSTEM BY REORGANIZATION OF THE ACTIN-FILAMENTS IN EHRLICH ASCITES TUMOR-CELLS

被引：62

作者：

JESSEN, F ^{[1
]}

HOFFMANN, EK ^{[1
]}

机构：

[1] UNIV COPENHAGEN,AUGUST KROGH INST,INST BIOL CHEM,DK-2100 COPENHAGEN,DENMARK

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1992年 / 1110卷 / 02期

关键词：

SODIUM POTASSIUM CHLORIDE COTRANSPORT; VOLUME REGULATION; ACTIN; MICROFILAMENT; CYTOCHALASIN-B; (EHRLICH ASCITES TUMOR CELL);

D O I：

10.1016/0005-2736(92)90359-T

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Reorganization (disassembly) of the actin filaments in Ehrlich ascites tumor cells, either by hypotonic treatment in the presence of Ca2+ or by addition of cytochalasin B, results in activation of the Na+/K+/Cl- cotransport system. However, other regulatory processes, some of which may be dependent on an intact filament system, are responsible for the activation of the Na+/K+/Cl- cotransport system after cell shrinkage.

引用

页码：199 / 201

页数：3

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