APLYSILLAMIDE-A AND APLYSILLAMIDE-B, NEW ANTIMICROBIAL GUANIDINE ALKALOIDS FROM THE OKINAWAN MARINE SPONGE PSAMMAPLYSILLA-PUREA

被引：20

作者：

HONMA, K

TSUDA, M

MIKAMI, Y

KOBAYASHI, J

机构：

[1] HOKKAIDO UNIV,FAC PHARMACEUT SCI,SAPPORO,HOKKAIDO 060,JAPAN

[2] CHIBA UNIV,PATHOGEN FUNGI & MICROBIAL TOXICOSES RES CTR,CHIBA 260,JAPAN

来源：

TETRAHEDRON | 1995年 / 51卷 / 13期

关键词：

D O I：

10.1016/0040-4020(95)00121-N

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two new guanidine alkaloids, aplysillamides A (1) and B (2), with antimicrobial activity have been isolated from the Okinawan marine sponge Psammaplysilla purea and the structures elucidated on the basis of spectroscopic data. The absolute stereochemistry at C-3 of Z was established as S by synthesis of 2.

引用

收藏

页码：3745 / 3748

页数：4

相关论文

共 10 条

[1] ACARNIDINES, NOVEL ANTI-VIRAL AND ANTI-MICROBIAL COMPOUNDS FROM SPONGE ACARNUS-ERITHACUS-(DE LAUBENFELS) [J].

CARTER, GT ;

RINEHART, KL .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1978, 100 (13) :4302-4304

[2]

DANKLMAIER J, 1990, LIEBIGS ANN CHEM, P145

[3] MARINE-INVERTEBRATES FROM NEO-CALEDONIAN LAGOONS .5. ISOLATION AND IDENTIFICATION OF METABOLITES FROM A NEW SPECIES OF SPONGE, PSEUDAXINYSSA-CANTHARELLA [J].

DENANTEUIL, G ;

AHOND, A ;

GUILHEM, J ;

POUPAT, C ;

DAU, ETH ;

POTIER, P ;

PUSSET, M ;

PUSSET, J ;

LABOUTE, P .

TETRAHEDRON, 1985, 41 (24) :6019-6033

[4]

KOBAYASHI J, IN PRESS CHEM PHARMB

[5]

KOBAYASHI J, IN PRESS J NAT PROD

[6] PHLOEODICTINE-A AND PHLOEODICTINE-B - NEW ANTIBACTERIAL AND CYTOTOXIC BICYCLIC AMIDINIUM SALTS FROM THE NEW CALEDONIAN SPONGE, PHLOEODICTYON SP [J].

KOURANYLEFOLL, E ;

PAIS, M ;

SEVENET, T ;

GUITTET, E ;

MONTAGNAC, A ;

FONTAINE, C ;

GUENARD, D ;

ADELINE, MT ;

DEBITUS, C .

JOURNAL OF ORGANIC CHEMISTRY, 1992, 57 (14) :3832-3835

[7] FURTHER-STUDIES ON THE USE OF THE THALLIUM SALT OF N-HYDROXYSUCCINIMIDE FOR THE PREPARATION OF SUCCINIMIDYL ESTERS [J].

PAQUET, A .

CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1979, 57 (20) :2775-2778

[8] THE STRUCTURES OF APLYSINAMISINE-I, APLYSINAMISINE-II, AND APLYSINAMISINE-III - NEW BROMOTYROSINE-DERIVED ALKALOIDS FROM THE CARIBBEAN SPONGE APLYSINA-CAULIFORMIS [J].

RODRIGUEZ, AD ;

PINA, IC .

JOURNAL OF NATURAL PRODUCTS, 1993, 56 (06) :907-914

[9] PUREALIDIN-D, A NEW PYRIDINE ALKALOID FROM THE OKINAWAN MARINE SPONGE PSAMMAPLYSILLA-PUREA [J].

TSUDA, M ;

SHIGEMORI, H ;

ISHIBASHI, M ;

KOBAYASHI, J .

TETRAHEDRON LETTERS, 1992, 33 (18) :2597-2598

[10] PUREALIDINS E-G, NEW BROMOTYROSINE ALKALOIDS FROM THE OKINAWAN MARINE SPONGE PSAMMAPLYSILLA-PUREA [J].

TSUDA, M ;

SHIGEMORI, H ;

ISHIBASHI, M ;

KOBAYASHI, J .

JOURNAL OF NATURAL PRODUCTS, 1992, 55 (09) :1325-1327