EFFECTS OF GANODERMA-LUCIDUM AND KRESTIN ON SUBSET T-CELL IN SPLEEN OF GAMMA-IRRADIATED MICE

被引：24

作者：

CHEN, WC ^{[1
]}

HAU, DM ^{[1
]}

WANG, CC ^{[1
]}

LIN, IH ^{[1
]}

LEE, SS ^{[1
]}

机构：

[1] NATL TSING HUA UNIV,INST RADIAT BIOL,HSINCHU,TAIWAN

来源：

AMERICAN JOURNAL OF CHINESE MEDICINE | 1995年 / 23卷 / 3-4期

关键词：

D O I：

10.1142/S0192415X95000341

中图分类号：

R [医药、卫生];

学科分类号：

10 ;

摘要：

Effects of Ganoderma lucidum (G1) and Krestin (PSK) extracts on spleen, thymus and splenocytes in gamma-irradiated mice were investigated in this study. ICR strain male mice were divided into five groups, Group A was the normal control. Group B, the experimental control, was treated with GI. Group C, the radiation treatment control, was treated with whole body exposure to 4 Gy gamma-irradiation (RT). Group D was treated with RT and G1. Group E was treated with RT and PSK. The dosage of G1 was 400 mg/day/kg body weight and PSK was 500 mg/day/kg body weight. Our results indicated that the relative thymus weight in groups D and E were higher than group C on day 28 after gamma-irradiation. Group D was the highest in all the experimental groups. CD4 and CD8 splenocytes in group D were higher than group C on days 7 and 28, GI was better than PSK in repairing the damage of subset T-cells in the spleen of gamma-irradiated mice.

引用

页码：289 / 298

页数：10