A FAMILY OF GLYCOLIPID LINKED PROTEINS IN EIMERIA-TENELLA

被引：10

作者：

GURNETT, A

DULSKI, P

HSU, J

TURNER, MJ

机构：

[1] Merck, Sharp and Dohme Research Laboratories, Rahway, NJ

来源：

MOLECULAR AND BIOCHEMICAL PARASITOLOGY | 1990年 / 41卷 / 02期

关键词：

Cross-reacting determinant; Eimeria; Glycolipid-linked protein; Membrane anchor;

D O I：

10.1016/0166-6851(90)90180-T

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A number of proteins in Eimeria tenella are shown to possess a carbohydrate similar to that found on the carboxyl terminus of the variant surface glycoprotein from Trypanosoma brucei. In trypanosomes, this carbohydrate is part of a glycolipid structure responsible for membrane attachment. In common with the variant surface glycoprotein and with other glycolipid linked proteins, the E. tenella proteins were shown to be hydrophobic. Treatment with a crude lipase preparation from T. brucei modifies these proteins to a water-soluble form. © 1990.

引用

页码：177 / 185

页数：9

共 32 条

[1]

BORDIER C, 1981, J BIOL CHEM, V256, P1604

[2] LEISHMANIA AND TRYPANOSOMA SURFACE GLYCOPROTEINS HAVE A COMMON GLYCOPHOSPHOLIPID MEMBRANE ANCHOR [J].