CONTROL OF RING-JUNCTION STEREOCHEMISTRY VIA RADICAL CYCLIZATION - A NEW CONSTRUCTION OF TRANS-HYDRINDANS

被引：40

作者：

SATOH, S ^{[1
]}

SODEOKA, M ^{[1
]}

SASAI, H ^{[1
]}

SHIBASAKI, M ^{[1
]}

机构：

[1] HOKKAIDO UNIV,FAC PHARMACEUT SCI,SAPPORO,HOKKAIDO 060,JAPAN

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1991年 / 56卷 / 07期

关键词：

D O I：

10.1021/jo00007a004

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Treatment of 7b with Bu3SnH in toluene containing Et3B at -30-degrees-C afforded trans-hydrindan 8b exclusively (97% yield, trans:cis = 100:0). Furthermore, exposure of 13a to Bu3SnH in the presence of Et3B at -30-degrees-C gave the trans angularly methylated hydrindan 14a in a highly stereocontrolled manner (87% yield, trans:cis = 95:5).

引用

页码：2278 / 2280

页数：3

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