THE CHANGES OF THYROID-HORMONE DURING PHARMACOLOGICAL TREATMENT OF PANIC DISORDER PATIENTS

被引：11

作者：

BALON, R ^{[1
]}

POHL, R ^{[1
]}

YERAGANI, VK ^{[1
]}

RAMESH, C ^{[1
]}

GLITZ, DA ^{[1
]}

机构：

[1] WAYNE STATE UNIV,DEPT PSYCHIAT,DETROIT,MI 48202

来源：

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY | 1991年 / 15卷 / 05期

关键词：

DIAZEPAM; IMIPRAMINE; PANIC DISORDER; THYROID HORMONES;

D O I：

10.1016/0278-5846(91)90049-7

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

1. Because imipramine has lowered T4 in uncontrolled studies we examined the effect of imipramine on serum thyroid levels in panic disorder patients in a double-blind placebo and diazepam treatment controlled study. 2. Treatment with imipramine (10 subjects) was associated with a significant decrease of T4 and FTI and treatment with diazepam (8 subject) was associated with a significant decrease of T4. However, there was no significant difference across treatment groups. 3. This finding suggests that previously reported decreases in thyroid hormones during antidepressant therapy may be due to nonspecific effects of treatment rather than to the drug itself.

引用

页码：595 / 600

页数：6

共 15 条

[1] THE HYPOTHALAMIC-PITUITARY-THYROID AXIS IN PSYCHIATRIC-PATIENTS AND HEALTHY-SUBJECTS .1.4. [J].