SPONTANEOUS VARIABILITY OF LEFT-VENTRICULAR EJECTION FRACTION ASSESSED WITH THE CARDIOSCINT

被引：4

作者：

BROADHURST, P ^{[1
]}

LIU, XJ ^{[1
]}

CASHMAN, PMM ^{[1
]}

RAFTERY, EB ^{[1
]}

LAHIRI, A ^{[1
]}

机构：

[1] NORTHWICK PK HOSP & CLIN RES CTR,DEPT CARDIOL,HARROW HA1 3UJ,MIDDX,ENGLAND

来源：

NUCLEAR MEDICINE COMMUNICATIONS | 1992年 / 13卷 / 05期

关键词：

D O I：

10.1097/00006231-199205000-00004

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

A miniature, non-imaging caesium iodide nuclear probe optically coupled to a photodiode (the 'Cardioscint') has been developed which, in conjunction with a modified personal computer, is capable of continuous on-line monitoring of left ventricular function and ST-segment level at the bedside. The purpose of this study was to assess the variability in ejection fraction over periods of time and to compare this variability with that of equilibrium gamma camera radionuclide ventriculography. Ten normal volunteers (nine male) of mean (S.D.) age 49 (10) years underwent semisupine radionuclide ventriculography using both gamma camera and Cardioscint in randomized order. The gamma camera recorded four consecutive acquisitions (mean of 7.2 min each) and the Cardioscint, using a 20 s acquisition time, recorded left ventricular function over 35 min per subject. The mean ejection fraction of the group by gamma camera was 52 (7)% and by Cardioscint was 54 (5)%. When the variability in ejection fraction by gamma camera was compared with the Cardioscint averaged over corresponding time periods (i.e. an average of 7.2 min), the mean coefficient of variation of the camera was 5.0% versus 2.9% for the probe system. Individual 20-s probe acquisitions over the total study duration (reflecting the short-term variability of the system) had a coefficient of variation of 5.1%. Thus the Cardioscint provides a stable continuous recording of ejection fraction. These volunteer data provide a basis for interpretation of data acquired in the clinical situation.

引用

页码：312 / 320

页数：9

共 31 条

[1]

Davies G.J., Bencivelli W., Fragasso G., Et al., Sequence and magnitude of ventricular volume changes in painful and painless myocardial ischaemia, Circulation, 78, pp. 310-319, (1988)

[2]

Davies G., Chierchia S., Crea F., Mongiardi F., Maseri A., Positive ergometrine test without ECG changes, Am J Cardiol, 49, (1982)

[3]

Haiat R., Desoutter P., Stoltz J.P., Angina Pectoris Without S.-T., Changes in patients with documented coronary heart disease, Am Heart J, 105, pp. 883-884, (1983)

[4]

Breisblatt W.M., Wieland F.L., McClain J.R., Tomlinson G., Burns M., Spaccavento L., Usefulness of ambulatory radionuclide monitoring of left ventricular function early after myocardial infarction for predicting residual myocardial ischaemia, Am. J Cardiol, 62, pp. 1005-1010, (1988)

[5]

Nademanee K., Intarachot V., Josephson M.A., Rieders D., Mody F.V., Singh B.N., Prognostic significance of silent myocardial ischaemia in patients with unstable angina, J am Coll Cardiol, 10, pp. 1-9, (1987)

[6]

Gottlieb S.O., Weisfeldt M.L., Ouyang P., Mellits E.D., Gerstenblith G., Silent ischaemia predicts infarction and death during two year follow-up of unstable angina, J am Coll Cardiol, 10, pp. 756-760, (1987)

[7]

Kaplan J.A., Wells P.M., Early diagnosis of myocardial ischaemia using the pulmonary arterial catheter, Anesth Analg, 60, pp. 789-793, (1981)

[8]

Lahiri A., Rodrigues E.A., Carboni G.P., Raftery E.B., Effects of long-term treatment with calcium antagonists on left ventricular diastolic function in stable angina and heart failure, Circulation, 81, pp. 130-138, (1990)

[9]

Smith J.S., Cahalan M.K., Benefiel D.J., Et al., Intra-operative detection of myocardial ischaemia in high risk patients: Electrocardiography versus two-dimensional echocardiography, Circulation, 72, pp. 1015-1021, (1985)

[10]

Wagner H.N., Wake R., Nickoloff E., Natarajan T.K., The nuclear stethoscope: A simple device for generation of left ventricular volume curves, Am. J Cardiol, 38, pp. 747-750, (1976)

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