OROSOMUCOID POLYMORPHISM IN FINNS, SWEDES AND SWEDISH SAAMIS

被引：13

作者：

FAN, CH

SIKSTROM, C

BECKMAN, G

BECKMAN, L

机构：

[1] Department of Medical Genetics, University of Umeå

来源：

HUMAN HEREDITY | 1993年 / 43卷 / 05期

关键词：

OROSOMUCOID TYPES; POLYMORPHISM; FINNS; SWEDES; SAAMIS;

D O I：

10.1159/000154144

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Genetic polymorphism of orosomucoid (ORM) was studied by isoelectric focusing and immunoblotting in Finns, Swedes and Swedish Saamis. The ORM2 locus was found to be monomorphic in all three ethnic groups. In the Swedish sample the frequency of the ORM1*2 allele (0.414) was within the range found in other European populations, whereas Finns (0.282) and Saamis (0.210) showed significantly lower ORM1*2 frequencies. The extremely low ORM1*2 frequency in the Saamis further underlines the genetic uniqueness of this population. The ORM1*2 frequency in Saamis resembles those in Asiatic Mongoloid populations, but this is unlikely to reflect an Asiatic influence, since the accumulated knowledge on genetic markers in the Saamis show no unequivocal evidence for an Asiatic influence in this population.

引用

页码：272 / 275

页数：4

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