RAPID-DETERMINATION OF HUMAN CYTOMEGALOVIRUS SUSCEPTIBILITY TO GANCICLOVIR DIRECTLY FROM CLINICAL SPECIMEN PRIMOCULTURES

被引：27

作者：

PEPIN, JM

SIMON, F

DUSSAULT, A

COLLIN, G

DAZZA, MC

BRUNVEZINET, F

机构：

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 1992年 / 30卷 / 11期

关键词：

D O I：

10.1128/JCM.30.11.2917-2920.1992

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We were able to rapidly determine the susceptibility of human cytomegalovirus to ganciclovir using a late antigen synthesis reduction assay directly on primocultures of clinical specimens. This test was compared with a conventional susceptibility assay which was performed with cell-free virus obtained after cytomegalovirus isolation and in vitro passages. Both tests produced similar results. The rapid test, unlike conventional assays, is able to provide a result within 5 days after receipt of the specimen and could thus play a direct role in the therapeutic decision.

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页码：2917 / 2920

页数：4

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