DEVELOPMENT INVITRO OF CYTOTOXIC LYMPHOCYTES AGAINST MURINE CYTOMEGALO-VIRUS

被引：8

作者：

HO, M ^{[1
]}

ASHMAN, RB ^{[1
]}

机构：

[1] AUSTRALIAN NATL UNIV,JOHN CURTIN SCH MED RES,DEPT MICROBIOL,CANBERRA 2601,ACT,AUSTRALIA

来源：

AUSTRALIAN JOURNAL OF EXPERIMENTAL BIOLOGY AND MEDICAL SCIENCE | 1979年 / 57卷 / AUG期

关键词：

D O I：

10.1038/icb.1979.42

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Lymphocytes cytotoxic for mouse embryo fibroblasts (MEF) infected with murine cytomegalovirus (MCMV) were produced by in vitro culture of 'memory' spleen cells with UV-irradiated, MCMV-infected, MEF. Cytotoxic lymphocytes were developed from spleen cells of mice 10 to 240 days after infection with MCMV. The cytotoxic cells carried the theta and Ly 2 antigens, and were H-2 restricted in the recognition of infected target cells.

引用

页码：425 / 428

页数：4

共 15 条

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