HIGHER RECURRENCE RATE AFTER CORONARY ANGIOPLASTY IN UNSTABLE ANGINA-PECTORIS

被引:7
作者
JOHANSSON, SR
EKSTROM, L
EMANUELSSON, H
机构
[1] Department of Cardiology, University of Göteborg, Sahlgrenska Hospital, Göteborg
关键词
D O I
10.1177/000331979104200403
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
Purpose: Recurrent stenosis after percutaneous transluminal coronary angioplasty (PTCA) is a significant problem, requiring repeat dilation in about one-third of all treated patients. Various clinical and procedure-related predictors have been proposed. Between 1983 and 1987, 257 patients underwent 322 procedures, where 380 stenoses were attempted. Indications were: stable angina pectoris 73%, unstable angina pectoris 22%, other indication 5%. The primary success rate was defined as a < 50% remaining postprocedure stenosis. Findings: Repeat angiograms were done for 88% of the initially successful cases, either six months after PTCA or if there was a clinical recurrence. Restenosis was defined as a recurrence of a more than 50% diameter stenosis. The restenosis rate was 33% and was significantly higher (p < 0.05) for unstable (46%) than for stable angina pectoris (29%). There was a nonsignificant tendency to a higher restenosis rate in the left anterior descending artery than in the other coronary vessels. Implications: The increased restenosis rate seen after PTCA for unstable angina pectoris could be caused by a higher activity in systems affecting the proliferative processes in the smooth muscle cells of the arterial wall, which is thought to form the pathophysiologic basis for restenosis after PTCA.
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页码:273 / 280
页数:8
相关论文
共 36 条
[1]   ANGIOGRAPHIC EVOLUTION OF CORONARY-ARTERY MORPHOLOGY IN UNSTABLE ANGINA [J].
AMBROSE, JA ;
WINTERS, SL ;
ARORA, RR ;
ENG, A ;
RICCIO, A ;
GORLIN, R ;
FUSTER, V .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1986, 7 (03) :472-478
[2]   ANGIOGRAPHIC DEMONSTRATION OF A COMMON LINK BETWEEN UNSTABLE ANGINA-PECTORIS AND NON-Q WAVE ACUTE MYOCARDIAL-INFARCTION [J].
AMBROSE, JA ;
HJEMDAHLMONSEN, CE ;
BORRICO, S ;
GORLIN, R ;
FUSTER, V .
AMERICAN JOURNAL OF CARDIOLOGY, 1988, 61 (04) :244-247
[3]   INTIMAL PROLIFERATION OF SMOOTH-MUSCLE CELLS AS AN EXPLANATION FOR RECURRENT CORONARY-ARTERY STENOSIS AFTER PERCUTANEOUS TRANS-LUMINAL CORONARY ANGIOPLASTY [J].
AUSTIN, GE ;
RATLIFF, NB ;
HOLLMAN, J ;
TABEI, S ;
PHILLIPS, DF .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1985, 6 (02) :369-375
[4]  
BERTRAND ME, 1987, BRIT HEART J, V58, P469
[5]   THE ELECTROCARDIOGRAM IN POPULATION STUDIES - A CLASSIFICATION SYSTEM [J].
BLACKBURN, H ;
KEYS, A ;
SIMONSON, E ;
RAUTAHARJU, P ;
PUNSAR, S .
CIRCULATION, 1960, 21 (06) :1160-1175
[6]   MEDICAL APPROACHES TO PREVENTION OF RESTENOSIS AFTER CORONARY ANGIOPLASTY [J].
BLACKSHEAR, JL ;
OCALLAGHAN, WG ;
CALIFF, RM .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1987, 9 (04) :834-848
[7]  
BOURASSA M G, 1988, European Heart Journal, V9, P1034
[8]   UNSTABLE ANGINA - A CLASSIFICATION [J].
BRAUNWALD, E .
CIRCULATION, 1989, 80 (02) :410-414
[9]  
COLTON T, 1974, STAT MED, P163
[10]  
DANGOISSE V, 1982, CIRCULATION, V66, P331