CRUDE DRUGS FROM AQUATIC PLANTS .3. QUANTITATIVE-ANALYSIS OF TRITERPENE CONSTITUENTS IN ALISMATIS RHIZOMA BY MEANS OF HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY ON THE CHEMICAL-CHANGE OF THE CONSTITUENTS DURING ALISMATIS RHIZOMA PROCESSING

被引：25

作者：

YOSHIKAWA, M ^{[1
]}

YAMAGUCHI, S ^{[1
]}

CHATANI, N ^{[1
]}

NISHINO, Y ^{[1
]}

MATSUOKA, T ^{[1
]}

YAMAHARA, J ^{[1
]}

MURAKAMI, N ^{[1
]}

MATSUDA, H ^{[1
]}

KUBO, M ^{[1
]}

机构：

[1] KINKI UNIV, FAC PHARMACEUT SCI, OSAKA 577, JAPAN

来源：

YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN | 1994年 / 114卷 / 04期

关键词：

ALISMATIS RHIZOMA; ALISMA ORIENTATE; AQUATIC PLANT; CRUDE DRUG PROCESSING; QUANTITATIVE HPLC ANALYSIS; TRITERPENE CONSTITUENT;

D O I：

10.1248/yakushi1947.114.4_241

中图分类号：

R9 [药学];

学科分类号：

1007 [药学];

摘要：

As a series of study on the evaluation of Alismatis Rhizoma and the chemical characterization of the processing, a quantitative method by high performance liquid chromatography (HPLC) for ten triterpene constituents, alisols A, A monoacetate, B, B monoacetate, E 23-acetate, F, and G and 13,17-epoxyalisol A, 11-deoxyalisols B and B 23-acetate, has been developed. By the use of this HPLC method, the contents of these triterpenes in various Alismatis Rhizoma and the fresh rhizoma of Alisma orientale JUZEPC. originaed from in China, Taiwan, and Japan were examined. Furthermore, the chemical change of the triterpene constituents during the drying process of the rhizoma of Alisma orientale has been investigated and it was found that the bioactive triterpenes of Alismatis Rhizoma such as alisol A and alisol A monoacetate were artificially formed during the drying process.

引用

页码：241 / 247

页数：7

共 16 条

[1]

11-DEOXYALISOL C AND ALISOL D - NEW PROTOSTANE-TYPE TRITERPENOIDS FROM ALISMA-PLANTAGO-AQUATICA [J].