BENIGN FORM OF MULTIPLE-SCLEROSIS - MRI EVIDENCE FOR LESS FREQUENT AND LESS INFLAMMATORY DISEASE-ACTIVITY

被引：37

作者：

KIDD, D ^{[1
]}

THOMPSON, AJ ^{[1
]}

KENDALL, BE ^{[1
]}

MILLER, DH ^{[1
]}

MCDONALD, WI ^{[1
]}

机构：

[1] UCL INST NEUROL, NATL HOSP, NMR RES GRP, LONDON WC1N 3BG, ENGLAND

来源：

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY | 1994年 / 57卷 / 09期

关键词：

D O I：

10.1136/jnnp.57.9.1070

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Data from two serial studies comparing the MRI activity of two groups of 11 patients, one with early relapsing-remitting (mean disease duration 3.5 years), the other benign (mean disease duration 22 years) multiple sclerosis are presented, Those with benign disease developed fewer new or enlarging lesions, and such lesions that occurred had a lower incidence of gadolinium enhancement, a marker of inflammation. These results, when considered in conjunction with other published studies, suggest that both the frequency of new lesions and the amount of inflammation within them influence the development of disability in multiple sclerosis.

引用

页码：1070 / 1072

页数：3

共 21 条

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