GLUCAGON-SENSITIVE ADENYL CYLASE IN PLASMA MEMBRANE OF HEPATIC PARENCHYMAL CELLS

被引：153

作者：

POHL, SL

BIRNBAUMER, L

RODBELL, M

机构：

[1] Laboratory of Nutrition and Endocrinology, National Institute of Arthritis and Metabolic Diseases, Bethesda

来源：

SCIENCE | 1969年 / 164卷 / 3879期

关键词：

D O I：

10.1126/science.164.3879.566

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The plasma membrane of hepatic parenchymal cells contains an adenyl cyclase system that is stimulated by glucagon. Adrenocorticotropin and epinephrine do not stimulate this adenyl cyclase, and very little cyclic phosphodiesterase activity is present in the membrane. These findings support the concept that glucagon exerts its regulatory action in the liver by stimulating adenyl cyclase activity in the plasma membrane.

引用

页码：566 / +

页数：1

共 13 条

[1] PLASMA MEMBRANES OF RAT LIVES - ISOLATION OF LIPOPROTEIN MACROMOLECULES [J].