HISTOCHEMICAL-DEMONSTRATION OF INTERLEUKIN-2 IN DECIDUA CELLS OF PATIENTS WITH PREECLAMPSIA

被引：40

作者：

HARA, N ^{[1
]}

FUJII, T ^{[1
]}

OKAI, T ^{[1
]}

TAKETANI, Y ^{[1
]}

机构：

[1] UNIV TOKYO,SCH MED,DEPT OBSTET & GYNECOL,BUNKYO KU,TOKYO 113,JAPAN

来源：

AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY | 1995年 / 34卷 / 01期

关键词：

CYTOKINE; INTERLEUKIN-2; PREECLAMPSIA; IMMUNOHISTOCHEMICAL STAINING;

D O I：

10.1111/j.1600-0897.1995.tb00918.x

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

PROBLEM: The objective of this study was to gain insight into the immunological aspects of preeclampsia. METHOD: The presence of interleukin-2 (IL-2) protein in the decidua was examined in five preeclamptic patients and seven normal pregnant women employing the immunohistochemistry. RESULTS: The decidua cells were strongly stained for IL-2 in four out of five preeclamptic patients, while only very weak, if any, staining was observed in all the uncomplicated pregnant women. CONCLUSIONS: IL-2 was clearly present in decidua cells in the preeclamptic setting, suggesting the possible involvement of immune-activation in the phathophysiology of preeclampsia.

引用

页码：44 / 51

页数：8

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