CIRCULATING MELATONIN IN MAN - EPISODIC SECRETION THROUGHOUT THE LIGHT-DARK CYCLE

被引：79

作者：

WEINBERG, U

DELETTO, RD

WEITZMAN, ED

ERLICH, S

HOLLANDER, CS

机构：

[1] MONTEFIORE HOSP & MED CTR, DEPT MED, BRONX, NY 10467 USA

[2] NYU, SCH MED, DEPT MED, DIV ENDOCRINE, NEW YORK, NY 10003 USA

来源：

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM | 1979年 / 48卷 / 01期

关键词：

D O I：

10.1210/jcem-48-1-114

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A sensitive and specific RIA for melatonin has been validated for human plasma. Five young adult men had plasma samples obtained every 20 min during two 24-h periods. One was a normal active period and the other a basal period with complete bed rest. Melatonin was found to be secreted episodically throughout the 24 h in each condition, with secretory episodes clearly present during the waking day in the presence of bright light. © 1979 by The Endocrine Society.

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页码：114 / 118

页数：5

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