NEW COMBINATION CHEMOTHERAPY FOR RESISTANT TROPHOBLASTIC DISEASE

被引：33

作者：

SURWIT, EA

SUCIU, TN

SCHMIDT, HJ

HAMMOND, CB

机构：

[1] The Southeastern Regional Center for Trophoblastic Disease, Department of Obstetrics and Gynecology, Duke University Medical Center, Durham

来源：

GYNECOLOGIC ONCOLOGY | 1979年 / 8卷 / 01期

关键词：

D O I：

10.1016/0090-8258(79)90016-7

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Six patients with gestational trophoblastic neoplasia resistant to triple chemotherapy (methotrexate, actinomycin D, and Cytoxan: MAC) treated with a new chemotherapeutic regimen (modified Bagshawe protocol: MBP) are presented. Five of the six patients are alive without evidence of recurrent disease with negative β-subunit human chorionic gonadotropin (HCG) titers from 2 to 18 months after completion of therapy. The MBP regimen would appear to be less toxic than triple chemotherapy (MAC) in this group of patients. A critical analysis of the MBP regimen is presented. © 1979.

引用

页码：110 / 118

页数：9

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