THE INVITRO AND INVIVO INHIBITION OF INTESTINAL HEME OXYGENASE BY TIN-PROTOPORPHYRIN

被引：23

作者：

ROSENBERG, DW ^{[1
]}

DRUMMOND, GS ^{[1
]}

KAPPAS, A ^{[1
]}

机构：

[1] ROCKEFELLER UNIV HOSP,1230 YORK AVE,NEW YORK,NY 10021

来源：

PHARMACOLOGY | 1989年 / 39卷 / 04期

关键词：

D O I：

10.1159/000138601

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：224 / 229

页数：6

共 22 条

[1]

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[2] DISPOSITION OF TIN-PROTOPORPHYRIN AND SUPPRESSION OF HYPERBILIRUBINEMIA IN HUMANS [J].

ANDERSON, KE ;

SIMIONATTO, CS ;

DRUMMOND, GS ;

KAPPAS, A .

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[3] PREVENTION OF NEONATAL HYPERBILIRUBINEMIA BY TIN PROTOPORPHYRIN-IX, A POTENT COMPETITIVE INHIBITOR OF HEME OXIDATION [J].

DRUMMOND, GS ;

KAPPAS, A .

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[4] METAL-ION INTERACTIONS IN THE CONTROL OF HEME OXYGENASE INDUCTION IN LIVER AND KIDNEY [J].

DRUMMOND, GS ;

KAPPAS, A .

BIOCHEMICAL JOURNAL, 1980, 192 (02) :637-648

[5] METABOLISM OF HEME AND BILIRUBIN IN RAT AND HUMAN SMALL INTESTINAL-MUCOSA [J].

HARTMANN, F ;

BISSELL, DM .

JOURNAL OF CLINICAL INVESTIGATION, 1982, 70 (01) :23-29

[6] LACK OF INHIBITION OF INTESTINAL HEME OXYGENASE BY ANTIBIOTICS AND TIN-PROTOPORPHYRIN [J].

HINTZ, SR ;

KIM, CB ;

VREMAN, HJ ;

STEVENSON, DK .

PEDIATRIC RESEARCH, 1988, 23 (01) :50-53

[7] CONTROL OF HEME METABOLISM WITH SYNTHETIC METALLOPORPHYRINS [J].

KAPPAS, A ;

DRUMMOND, GS .

JOURNAL OF CLINICAL INVESTIGATION, 1986, 77 (02) :335-339

[8]

LOWRY OH, 1951, J BIOL CHEM, V193, P265

[9]

MAINES MD, 1975, J BIOL CHEM, V250, P4171

[10] COBALT INDUCTION OF HEPATIC HEME OXYGENASE WITH EVIDENCE THAT CYTOCHROME-P-450 IS NOT ESSENTIAL FOR THIS ENZYME-ACTIVITY [J].

MAINES, MD ;

KAPPAS, A .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1974, 71 (11) :4293-4297

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