LOCALIZATION OF THE PROPERDIN FACTOR COMPLEMENT LOCUS PFC TO BAND-A3 ON THE MOUSE X-CHROMOSOME

被引：6

作者：

EVANS, EP

BURTENSHAW, MD

LAVAL, SH

GOUNDIS, D

REID, KBM

BOYD, Y

机构：

[1] MRC,RADIOBIOL UNIT,DIV GENET,DIDCOT OX11 0RD,OXON,ENGLAND

[2] DEPT BIOCHEM,MRC,IMMUNOCHEM UNIT,OXFORD,ENGLAND

[3] UNIV OXFORD,OXFORD OX1 3RE,ENGLAND

来源：

GENETICAL RESEARCH | 1990年 / 56卷 / 2-3期

关键词：

D O I：

10.1017/S0016672300035230

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The locus for properdin (properdin factor complement, Pfc), a plasma glycoprotein, has been mapped to band A3 of the mouse X chromosome by in situ hybridization to metaphase spreads containing an X;2 Robertsonian translocation. The X-linkage of the locus has also been confirmed by analysis of Mus musculus x Mus spretus interspecific crosses. The XA3 localization for Pfc places it in the chromosomal segment conserved between man and mouse which is known to contain at least six other homologous loci (Cybb, Otc, Syn-1 Maoa, Araf, Timp). © 1990, Cambridge University Press. All rights reserved.

引用

页码：153 / 155

页数：3

共 16 条

[1] THE INFLUENCE OF THE ROBERTSONIAN TRANSLOCATION RB(X.2)2AD ON ANAPHASE-I NON-DISJUNCTION IN MALE LABORATORY MICE [J].