SUCCESSFUL THERAPY FOR CEREBRAL PHEOHYPHOMYCOSIS DUE TO DACTYLARIA-GALLOPAVA IN A LIVER-TRANSPLANT RECIPIENT

被引：46

作者：

VUKMIR, RB

KUSNE, S

LINDEN, P

PASCULLE, W

FOTHERGILL, AW

SHEAFFER, J

NIETO, J

SEGAL, R

MERHAV, H

MARTINEZ, AJ

RINALDI, MG

机构：

[1] UNIV PITTSBURGH, MED CTR, DEPT ANESTHESIOL & CRIT CARE MED, DIV INFECT DIS, PITTSBURGH, PA 15213 USA

[2] UNIV PITTSBURGH, MED CTR, DEPT ANESTHESIOL & CRIT CARE MED, PITTSBURGH, PA USA

[3] UNIV PITTSBURGH, MED CTR, DEPT ANESTHESIOL & CRIT CARE MED, PITTSBURGH, PA USA

[4] UNIV PITTSBURGH, MED CTR, DEPT INFECT DIS, PITTSBURGH, PA USA

[5] UNIV PITTSBURGH, MED CTR, DEPT NEUROL SURG, PITTSBURGH, PA USA

[6] UNIV PITTSBURGH, MED CTR, DEPT PATHOL, PITTSBURGH, PA USA

[7] UNIV PITTSBURGH, MED CTR, DEPT SURG, PITTSBURGH, PA USA

[8] UNIV PITTSBURGH, MED CTR, CLIN MICROBIOL LAB, PITTSBURGH, PA USA

[9] UNIV TEXAS, HLTH SCI CTR, SAN ANTONIO, TX USA

来源：

CLINICAL INFECTIOUS DISEASES | 1994年 / 19卷 / 04期

关键词：

D O I：

10.1093/clinids/19.4.714

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A 68-year-old liver transplant recipient who was being treated with FK 506 and immunosuppressive steroid therapy was admitted to our medical center because of a tonic-clonic seizure. Computed tomography of the head revealed multiple discrete cerebral abscesses, and culture of fluid drained intraoperatively yielded a dematiaceous fungus. The isolate was susceptible to amphotericin B and itraconazole but was resistant to flucytosine and fluconazole. The patient was successfully treated with a prolonged course of amphotericin B colloidal dispersion and itraconazole, as evidenced by both clinical and radiographic resolution of disease over a 2-year follow-up.

引用

页码：714 / 719

页数：6

共 25 条

[1] GENERIC CONCEPTS OF DIPLORHINOTRICHUM AND DACTYLARIA AND A NEW SPECIES OF DACTYLARIA FROM SOIL [J].