Free radical cyclization of acyclic sugar dithioacetals: An approach to mannostatin a analogues

被引：9

作者：

Marco-Contelles, Jose ^{[1
]}

Destabel, Christine ^{[1
]}

Gallego, Pilar ^{[1
]}

机构：

[1] CSIC, Inst Quim Organ Gen, E-28006 Madrid, Spain

来源：

JOURNAL OF CARBOHYDRATE CHEMISTRY | 1995年 / 14卷 / 09期

关键词：

D O I：

10.1080/07328309508005415

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The tributyltin hydride + AIBN mediated free radical cyclization of oxime ethers tethered dithioacetals 6 and 12, obtained from D-ribose or D-glucose, respectively, is reported. The desired carbocycles 7, s and 14 have been obtained in good yield and moderate diastereoselectivity. These products are new mannostatin A analogues.

引用

页码：1343 / 1352

页数：10

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