THE THEORETICAL-ANALYSIS OF THE PROCESS OF RNA MOLECULE SELF-ASSEMBLY

被引：8

作者：

KISTER, A ^{[1
]}

MAGARSHAK, Y ^{[1
]}

MALINSKY, J ^{[1
]}

机构：

[1] CUNY MT SINAI SCH MED, NEW YORK, NY 10029 USA

来源：

BIOSYSTEMS | 1993年 / 30卷 / 1-3期

关键词：

D O I：

10.1016/0303-2647(93)90060-P

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The Kinetic approach to the problem of the RNA structure prediction based on the analysis of the molecule self-formation is proposed. Re-structurization that occurs during processing is described in terms of Markov processes. A new formalism designating nucleotides by complex numbers is proposed, leading to the complex unitary space of nucleic vectors. Properties of structure and transition matrices are discussed in relation to the analysis of RNA structural formation processes. The non-linear dynamic behavior of secondary structure transitions is analyzed. Soliton-like oscillations of RNA and DNA tertiary structures are predicted. The Monte-Carlo simulation of the RNA structure self-formation is used to calculate the ensemble of the secondary structures of the tRNA(Ala) precursor from Bombix mori formed during processing.

引用

页码：31 / 48

页数：18

共 33 条

[1] EFFICIENT ALGORITHMS FOR FOLDING AND COMPARING NUCLEIC-ACID SEQUENCES [J].