SYNTHESIS OF (ALPHA,ALPHA-DIFLUOROALKYL)PHOSPHONATES BY DISPLACEMENT OF PRIMARY TRIFLATES

被引：124

作者：

BERKOWITZ, DB

EGGEN, M

SHEN, Q

SLOSS, DG

机构：

[1] Department of Chemistry, University of Nebraska-Lincoln, Lincoln

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1993年 / 58卷 / 23期

关键词：

D O I：

10.1021/jo00075a005

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Simple primary alkyl triflates and those derived from several monosaccharides are cleanly displaced by diethyl (lithiodifluoromethyl)phosphonate to provide the corresponding (alpha,alpha-difluoroalkyl)phosphonates in minutes at -78-degrees-C.

引用

页码：6174 / 6176

页数：3

共 21 条

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