1992 BADER,ALFRED AWARD LECTURE - PROBING THE SPECIFICITY OF SYNTHETICALLY USEFUL ENZYMES

被引：8

作者：

JONES, JB

机构：

来源：

CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE | 1993年 / 71卷 / 09期

关键词：

D O I：

10.1139/v93-164

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Factors involved in controlling and predicting the structural specificity and stereospecificity of synthetically useful enzymes, including pig liver esterase, subtilisin BPN' and Carlsberg, alpha-chymotrypsin, and an L-lactate dehydrogenase, are discussed.

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页码：1273 / 1282

页数：10

相关论文

共 30 条

[1] CLONING, EXPRESSION AND COMPLETE NUCLEOTIDE-SEQUENCE OF THE BACILLUS-STEAROTHERMOPHILUS L-LACTATE DEHYDROGENASE GENE [J].

BARSTOW, DA ;

CLARKE, AR ;

CHIA, WN ;

WIGLEY, D ;

SHARMAN, AF ;

HOLBROOK, JJ ;

ATKINSON, T ;

MINTON, NP .

GENE, 1986, 46 (01) :47-55

[2]

BOONEAU PR, 1990, J AM CHEM SOC, V113, P1026

[3]

BOUTELJE J, 1987, BIOCATALYSIS ORGANIC

[4]

CHENEVERT R, 1989, SYNTHESIS-STUTTGART, P444

[5]

CROUT DHG, 1989, MOD SYN MET, V5, P1

[6]

DAVIES HG, 1990, BIOTRANSFORMATIONS P

[7]

Holbrook JJ, 1975, ENZYMES A, VXI, P191

[8] CRYSTALLIZATION AND PRELIMINARY-X-RAY DIFFRACTION STUDIES OF 2 MUTANTS OF LACTATE-DEHYDROGENASE FROM BACILLUS-STEAROTHERMOPHILUS [J].

KUI, HA ;

KODANDAPANI, R ;

KALLWASS, H ;

HOGAN, JK ;

PARRIS, W ;

FRIESEN, JD ;

GOLD, M ;

JONES, JB ;

JAMES, MNG .

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 1992, 13 (02) :158-161

[9] ENZYMES IN ORGANIC-SYNTHESIS [J].

JONES, JB .

TETRAHEDRON, 1986, 42 (13) :3351-3403

[10] EFFECTS OF GLN102ARG AND CYS97GLY MUTATIONS ON THE STRUCTURAL SPECIFICITY AND STEREOSPECIFICITY OF THE L-LACTATE DEHYDROGENASE FROM BACILLUS-STEAROTHERMOPHILUS [J].

KALLWASS, HKW ;

LUYTEN, MA ;

PARRIS, W ;

GOLD, M ;

KAY, CM ;

JONES, JB .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1992, 114 (12) :4551-4557