BIMODAL RELEASE OF IBUPROFEN IN A SUSTAINED-RELEASE FORMULATION - A SCINTIGRAPHIC AND PHARMACOKINETIC OPEN STUDY IN HEALTHY-VOLUNTEERS UNDER DIFFERENT CONDITIONS OF FOOD-INTAKE

被引：83

作者：

WILSON, CG ^{[1
]}

WASHINGTON, N ^{[1
]}

GREAVES, JL ^{[1
]}

KAMALI, F ^{[1
]}

REES, JA ^{[1
]}

SEMPIK, AK ^{[1
]}

LAMPARD, JF ^{[1
]}

机构：

[1] BOOTS CO LTD,RES DEPT,NOTTINGHAM NG2 3AA,ENGLAND

来源：

INTERNATIONAL JOURNAL OF PHARMACEUTICS | 1989年 / 50卷 / 02期

关键词：

D O I：

10.1016/0378-5173(89)90140-3

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：155 / 161

页数：7

共 9 条

[1] A COMPARATIVE-STUDY OF THE GASTROINTESTINAL TRANSIT OF A PELLET AND TABLET FORMULATION [J].

DAVIS, SS ;

HARDY, JG ;

TAYLOR, MJ ;

WHALLEY, DR ;

WILSON, CG .

INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1984, 21 (02) :167-177

[2]

GLASS RC, 1974, BR J CLIN PHARM, V6, pP453

[3]

HELLER J, 1980, CONTROLLED RELEASE B, P8

[4] MECHANISM OF SUSTAINED-ACTION MEDICATION - THEORETICAL ANALYSIS OF RATE OF RELEASE OF SOLID DRUGS DISPERSED IN SOLID MATRICES [J].

HIGUCHI, T .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1963, 52 (12) :1145-&

[5] CORRELATION OF IBUPROFEN BIOAVAILABILITY WITH GASTROINTESTINAL TRANSIT BY SCINTIGRAPHIC MONITORING OF ER-171-LABELED SUSTAINED-RELEASE TABLETS [J].

PARR, AF ;

BEIHN, RM ;

FRANZ, RM ;

SZPUNAR, GJ ;

JAY, M .

PHARMACEUTICAL RESEARCH, 1987, 4 (06) :486-489

[6]

SHAH AC, 1988, ORAL SUSTAINED RELEA

[7] PHARMACOKINETICS AND INVIVO SCINTIGRAPHIC MONITORING OF A SUSTAINED-RELEASE ACETYLSALICYLIC-ACID FORMULATION [J].

WILSON, CG ;

PARR, GD ;

KENNERLEY, JW ;

TAYLOR, MJ ;

DAVIS, SS ;

HARDY, JG ;

REES, JA .

INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1984, 18 (1-2) :1-8

[8] ASSESSMENT OF DISINTEGRATION AND DISSOLUTION OF DOSAGE FORMS INVIVO USING GAMMA SCINTIGRAPHY [J].

WILSON, CG ;

WASHINGTON, N .

DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 1988, 14 (2-3) :211-281

[9] THE INFLUENCE OF FOOD ON THE ABSORPTION OF ACYCLOVIR - A PHARMACOKINETIC AND SCINTIGRAPHIC ASSESSMENT [J].

WILSON, CG ;

WASHINGTON, N ;

HARDY, JG ;

BOND, SW .

INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1987, 38 (1-3) :221-225

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