MULTIPOINT LINKAGE MAPPING OF THE EMERY-DREIFUSS MUSCULAR-DYSTROPHY GENE

被引：11

作者：

KRESS, W

MULLER, E

KAUSCH, K

KULLMANN, F

MOSTACCIUOLO, ML

RIETSCHEL, M

ROTTHAUWE, HW

SCHMALENBERGER, B

SICILIANO, G

VOIT, T

LANGENBECK, U

MULLUER, B

DANIELI, GA

ZERRES, K

MULLER, CR

GRIMM, T

机构：

[1] UNIV WURZBURG, INST HUMAN GENET, W-8700 WURZBURG, GERMANY

[2] UNIV PADUA, DIPARTIMENTO BIOL, I-35100 PADUA, ITALY

[3] UNIV BONN, INST HUMAN GENET, W-5300 BONN, GERMANY

[4] UNIV BONN, KINDERKLIN, W-5300 BONN, GERMANY

[5] UNIV PISA, DIPARTIMENTO NEUROL, I-56100 PISA, ITALY

[6] UNIV DUSSELDORF, KINDERKLIN, W-4000 DUSSELDORF 1, GERMANY

[7] UNIV FRANKFURT, INST HUMAN GENET, W-6000 FRANKFURT, GERMANY

[8] UNIV MUNICH, PADIAT GENET ABT, W-8000 MUNICH 2, GERMANY

来源：

NEUROMUSCULAR DISORDERS | 1992年 / 2卷 / 02期

关键词：

EMERY-DREIFUSS MUSCULAR DYSTROPHY; LINKAGE ANALYSIS; X-LINKED MUSCULAR DYSTROPHY;

D O I：

10.1016/0960-8966(92)90042-5

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The clinical features to establish the diagnosis of X-linked Emery Dreifuss muscular dystrophy (EMD) were recently redefined at the European EMD workshop in Baarn 1991. These criteria were used to select families from the literature and two new families for linkage analysis with the DNA markers F9, DX52, DXS15, F8C and DXS115. Recombinations are observed with the DNA markers F9, DXS52 and DXS15. No recombinations were found with F8C and DXS115. Multipoint linkage analysis indicates with a maximum location score of 73.9 that the EMD locus maps very close to F8C.

引用

页码：111 / 115

页数：5

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