A NEW GROUP OF ISOQUINOLINE DIMERS FROM HERNANDIA-VOYRONII

被引：7

作者：

RASOANAIVO, P

RATSIMAMANGAURVERG, S

GALEFFI, C

NICOLETTI, M

FRAPPIER, F

MARTIN, MT

机构：

[1] INST MALGACHE RECH APPL, ANTANANARIVO 101, MADAGASCAR

[2] IST SUPER SANITA, CHIM FARMACO LAB, I-00161 ROME, ITALY

[3] UNIV ROMA LA SAPIENZA, DIPARTIMENTO BIOL VEGETALE, I-00185 ROME, ITALY

[4] MUSEUM NATL HIST NAT, CNRS, CHIM LAB, URA 401, F-75231 PARIS 05, FRANCE

来源：

TETRAHEDRON | 1995年 / 51卷 / 04期

关键词：

D O I：

10.1016/0040-4020(94)00992-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学]; 081704 [应用化学];

摘要：

As guided by bioassay to reverse chloroquine resistance in strains of Plasmodium falciparum, three bisisoquinoline alkaloids pertaining to a novel group, the pavine-benzyltatrahydroisoquinoline dimers, were isolated from stem barks of Hernandia voyromii Jumelle. Their chemical structures were determined by conventional spectral methods assisted by the performance of the 2D NMR techniques, namely COSY LR, HMQC and HMBC.

引用

页码：1221 / 1228

页数：8

共 12 条

[1]

CAPURON R, 1966, ADANSONIA, V3, P375

[2]

HARADA N, 1983, CIRCULAR DICHROISM S, P286

[3]

ALKALOIDS OF ANNONACEAE .37. ALKALOIDS OF GUATTERIA-SCANDENS [J].