IMMUNOPATHOLOGIC AND HISTOLOGIC-STUDIES ON SKIN FROM PEMPHIGUS PATIENTS IN TISSUE-CULTURE

被引：4

作者：

CHORZELSKI, TP

ROGOZINSKI, T

SULEJ, J

机构：

[1] Department of Dermatology, Medical Academy, Warsaw

来源：

JOURNAL OF CUTANEOUS PATHOLOGY | 1979年 / 6卷 / 02期

关键词：

D O I：

10.1111/j.1600-0560.1979.tb01114.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Explants of skin from patients with pemphigus vulgaris and pemphigus foliaceus taken in the active stages of the disease had in vivo bound IgG in the intercellular area. After 24–48 h incubation of these explants in normal sera acantholytic bullae developed above the stratum basale, thus indicating that the bound IgG is probably in vivo bound pemphigus antibody. In both cases, skin from the inactive stage of the disease contained no in vivo bound pemphigus antibodies. Explants of these skin specimens failed to develop acantholysis in culture. Copyright © 1979, Wiley Blackwell. All rights reserved

引用

页码：130 / 133

页数：4

共 10 条

[1]

BEUTNER EH, 1964, P SOC EXP BIOL MED, V117, P505

[2]

BEUTNER EH, 1973, IMMUNOPATHOLOGY SKIN, P330

[3]

BINDER WL, 1978, BRIT J DERMATOL, V99, P39, DOI 10.1111/j.1365-2133.1978.tb01958.x

[4] CLINICAL SIGNIFICANCE OF AUTOANTIBODIES IN PEMPHIGUS [J].