STEREOSELECTIVE AND REGIOSELECTIVE METAL SALT-CATALYZED ALKYNYLATION OF 1,2-EPOXIDES

被引：15

作者：

CHINI, M ^{[1
]}

CROTTI, P ^{[1
]}

FAVERO, L ^{[1
]}

MACCHIA, F ^{[1
]}

机构：

[1] UNIV PISA,DIPARTIMENTO CHIM BIOORGAN,VIA BONANNO 33,I-56126 PISA,ITALY

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 45期

关键词：

D O I：

10.1016/0040-4039(91)80237-Z

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple, efficient, stereoselective, and highly regioselective method for the synthesis of beta-hydroxyacetylenes by the direct opening of 1,2-epoxides with lithium acetylides in anhydrous THF, in the presence of metal salts, is described. This new method appears to be competitive and alternative to the other methods previously reported.

引用

页码：6617 / 6620

页数：4

共 29 条

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