COMPARATIVE-STUDIES OF IMMOBILIZED ENZYME ELECTRODES BASED ON THE INHIBITORY EFFECT OF NICOTINE ON CHOLINE OXIDASE AND ACETYLCHOLINESTERASE

被引：30

作者：

NWOSU, TN

PALLESCHI, G

MASCINI, M

机构：

[1] UNIV ROMA TOR VERGATA,DIPARTIMENTO SCI & TECNOL CHIM,VIA O RAIMONDO,I-00173 ROME,ITALY

[2] OBAFEMI AWOLOWO UNIV,DEPT CHEM,IFE,NIGERIA

[3] UNIV FIRENZE,DIPARTIMENTO SANITA PUBBL,EPIDEMIOL & CHIM ANALIT AMBIENTALE,I-50127 FLORENCE,ITALY

来源：

ANALYTICAL LETTERS | 1992年 / 25卷 / 05期

关键词：

NICOTINE; ENZYME ELECTRODE; AMPEROMETRY; INHIBITION; CHOLINE OXIDASE; ACETYLCHOLINESTERASE;

D O I：

10.1080/00032719208020039

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The inhibitory effect of nicotine on the activity of choline oxidase immobilized on nylon net has been investigated. Nicotine was found to inhibit choline oxidase in a manner similar to its effect on acetylcholinesterase. A nicotine - sensitive probe was realised via nicotine inhibition of choline oxidase. No appreciable difference in this biosensor performance and the performance of nicotine probe incorporating acetylcholinesterase coimmobilized with choline oxidase was observed.

引用

页码：821 / 835

页数：15

共 8 条

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